For g, n=4 independent experiments; values are normalized to untreated cells (=1.0). And thus, our love story has a happy ending: lovers from two hostile families have joined together inunity. On this Wikipedia the language links are at the top of the page across from the article title. Extended Data Fig. To subscribe to this RSS feed, copy and paste this URL into your RSS reader. Exothermic reactions occur when bonds are formed. Edited by G. Brauer, Academic Press, 1963, NY. 8 Reactive oxygen species production by excess selenium, and implications in SEPHS2 KO toxicity. 17, 4564 (1994). pH of Common Acids and Bases. Once the tip of the burette is full of solution, close the tap and add more solution up to the zero mark. The right hand panels are magnifications of the regions outlined by the white square. | 21 194, 499508 (2012). Therefore, it is classified as a hazardous waste and must be disposed of properly. Electronic configuration. And now lets visit the best of restaurants you decide which! ae, Representative flow cytometry data to address gating and quadrant strategy for FACS measurement of dying/dead cells. It is an induced solubility, as it were, That's right -- the new compound doesn't revert to the sodium salt after accepting the proton. You wont find the country of Chemistry on a world map, but it exists nonetheless. Biophys. Nutr. Cavalieri, R. R., Scott, K. G. & Sairenji, E. Selenite (75Se) as a tumor-localizing agent in man. Understand hydrochloric acid and sodium hydroxide and steps to neutralize hydrochloric acid with sodium hydroxide. What are the chemical reactions that have NaCl (sodium chloride) as product? It's a precipitation reaction much like what you've probably learned before, just now in the class of organic salts, not metallic salts. Slowly add HCl to cold water until it reaches a 1:10 dilution of acid to water. So if the Chemists intend to have dealings with them, they must protect themselves as best they can: they have no recourse but to work with them in a fume hood, and wear a lab coat, apron, gloves, special boots, and glasses or a protectiveshield. Jiang, L. et al. Under the microscope (if possible, a stereomicroscope is best) you can see the cubic nature of the crystals. Sodium sulfide, or Na2S, is an inorganic chemical compound with the formula of Na2S that has risen to prominence in the organic chemical industry. Includes kit list and safety instructions. For all panels, the measure of center is mean. Investigate reactions between acids and bases; use indicators and the pH scale. 404, 115120 (2007). Producing a neutral solution free of indicator, should take no more than 10 minutes. Is it known that BQP is not contained within NP? Modern burettes with PTFE stopcocks are much easier to use, require no greasing, and do not get blocked. For a,b, n=3 biological replicates; error bars are S.D. Breast and other cancer cells are selenophilic, owing to a secondary function of the cystine/glutamate antiporter SLC7A11 that promotes selenium uptake and selenocysteine biosynthesis, which, by allowing production of selenoproteins such as GPX4, protects cells against ferroptosis. An simple exchange of ions has taken place. The concentration of the solution does not need to be made up to a high degree of accuracy, but should be reasonably close to the same concentration as the sodium hydroxide solution, and less than 0.5 M. Methyl orange indicator solution (the solid is TOXICbut not the solution) see CLEAPSSHazcardHC032and CLEAPSSRecipe Book RB000. g, Viability of MDAMB231 cells in the numbered spots outlined on the 96 well plate, exposed to selenide gas. Sodium hydroxide can be used to neutralize HCl. Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis. Biometrika 69, 553566 (1982). Is it suspicious or odd to stand by the gate of a GA airport watching the planes? For all panels, *p<0.05 (students two-tailed t test). Sanjana, N. E., Shalem, O. 202 lessons This experiment will not be successful if the burettes used have stiff, blocked or leaky stopcocks. All of these are of course desirable traits to be developed in students, but there has to be some degree of basic competence and reliability before using a burette with a class. Sodium selenite is the inorganic compound with the formula Na2SeO3. This work was supported by the Suh Kyungbae Foundation (SUHF) Young Investigator Award to D.K. Toxicology 157, 310 (2001). Then the following steps should be followed: The reaction between an acid and base is exothermic. pH was adjusted to 4 by addition of hydrochloric acid with constant stirring . Baking soda is also classified as a base. Scale bar is 100m. When equal amounts are mixed, the result is a neutral substance, salt water. Watching solutions evaporate can be tedious for students, and they may need another task to keep them occupied eg rinsing and draining the burettes with purified water. The reaction was inhibited by mannitol, a hydroxyl radical quencher, but not by superoxide dismutase or catalase, strongly suggesting the involvement of hydroxyl radicals and ruling out participations of superoxide anions or hydrogen peroxide. InChI=1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2, InChI=1/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2, Except where otherwise noted, data are given for materials in their. Values are relative to the cells cultured in 100% growth media, set at 1.0. e, Immunoblot of FPS1 and catalase in SEPHS2 KO sensitive and in sensitive cell lines. The hydrate converts to the anhydrous salt upon heating to 40C. a, Validation of SEPHS2 RNA probe by RNAscope in situ hybridization in MDA231 cell pellet block samples. Do not boil dry. conducted mining and analyses of TCGA and other large-scale datasets. Alim, I. et al. SEPHS2 expression was compared in tumor and normal breast samples from TCGA b, and METABRIC (c) datasets. For a,c,e, n=3 biological replicates; error bars are S.D. However, this activity also becomes a liability for cancer cells because selenide is poisonous and must be processed by SEPHS2. Hydrochloric acid has a pH of 3 and is a component of stomach acid. What are the chemical reactions that have H2Se (Dihydrido selenium; Dihydrogen selenide; Hydrogen selenide; Selenium hydride; Dihydridoselenium) as product? e, Immunoblots of CAT and SEPHS2 in U251 and MDAMB231 cells overexpressing blank vector or CAT and subjected to KO with guides against SEPHS2 for 9 days. In order to neutralize HCl, there must be equivalent amounts of hydrogen and hydroxide ions formed. C5.4 How are the amounts of substances in solution measured? You can find a safer method for evaporating the solution along with technician notes, integrated instructions and an associated risk assessment activity for learners here. Chemical Substance Systematic Name: Sodium selenide (Na2Se) IUPAC Name: Disodium selenide CAS Number: 1313-85-5 EPA Registry Name: Sodium selenide (Na2Se) Molecular Weight: 124.94 Molecular Formula: Na2Se Additional Metadata For more information about the substance, you may click one of the links below to take you to the relevant section: HCl + NaOH = NaCl + HO + Q Hydrochloric acid and sodium hydroxide interact, resulting in salt and a release of heat. et al. An interaction with silver nitrate serves as a qualitative reaction to test for hydrochloric acid and itssalts. This resource also includes a redox titration experiment. In order to tell when the sodium hydroxide has completely reacted with all of the hydrochloric acid, we just need to monitor the pH. The micronutrient selenium is incorporated via the selenocysteine biosynthesis pathway into the rare amino acid selenocysteine, which is required in selenoproteins such as glutathione peroxidases and thioredoxin reductases1,2. If we're not careful, it could cause burns. Kim, J. Y. et al. To understand the full extent of the tragedy, lets get better acquainted with them and examine the nature of sodium hydroxide and hydrochloric acid. Sodium selenite is a precursor of Sec biosynthesis, and supplement of cells with Na 2 SeO 3 could significantly increases the Sec level in cells (Kryukov et al., 2003). Gating strategy is outlined in Extended Data Fig. Sodium hydroxide solution, NaOH(aq), (IRRITANT at concentration used) see CLEAPSS HazcardHC091a and CLEAPSS Recipe BookRB085. In order to calculate how much sodium hydroxide is needed to neutralize hydrochloric acid, the molarity of each must be known. The studies on the selective synthesis of dialkyl selenide compounds 1 were presented. Values are relative to the cells cultured in normoxic condition (20% O2), set at 1.0. d, Viability of control, SEPHS2, GPX4, and SEPSECS deficient MDAMB231 cells under nutrient starved conditions (10% growth media) for 48hr. Its like a teacher waved a magic wand and did the work for me. Get what matters in cancer research, free to your inbox weekly. An error occurred trying to load this video. Sodium Hydroxide Formula, Structure & Symbol | What is NaOH? This is because both products in the reaction are neutral. BMC Plant Biology Comprehensive molecular portraits of invasive lobular breast. Bernd E. Langner "Selenium and Selenium Compounds" in Ullmann's Encyclopedia of Industrial Chemistry (published on-line in 2000) Wiley-VCH, Weinheim, 2002, https://en.wikipedia.org/w/index.php?title=Sodium_selenite&oldid=1084200558, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Chemical articles with multiple CAS registry numbers, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 23 April 2022, at 03:44. Molarity is defined as the number of moles in a liter of solution. Google Scholar. Food Addit. We can then simply determine the volume of base needed in order to have the same number of moles of hydroxide and hydrogen ions. By using pH paper or a pH meter during the process, we can ensure that we end up with a neutral solution, which can be safely disposed of. In order to neutralize hydrochloric acid with sodium hydroxide, the following steps must be followed: Neutralization reactions are classified as exothermic reactions. Burk, R. F. & Hill, K. E. Regulation of selenium metabolism and transport. The acid and base react to form a neutral solution of water and a salt, defined as any positive and negative ion bonded with an ionic bond. In any laboratory where safety rules are observed and respected, alkalis and their ilk are kept strictly separate from acids and their ilk. This hydrolysis occurs because of the extreme basicity of the Se2 ion. CAS ).It involves: (i) the formation of sodium diselenide, leaving unreacted half of the amount of the sodium hydride introduced (Scheme 6, step a) Or if any of the following reactant substances Values are relative to the cell lines expressing nontargeting (CTRL) guide, set at 1.0. We therefore proposed an alternative pathway (Scheme 6 instead of Scheme 5), to explain the formation of dialkyl selenides 3 on sequential addition on elemental selenium of sodium hydride (2 equiv.) Cr2O3: PbCl4: Na3PO4: Na3PO4: SrSO4: Write the chemical formulas for the given compounds. Use a model, feedback, reapply loop to develop students practical skills, Practical experiment where learners produce gold coins by electroplating a copper coin with zinc, includes follow-up worksheet. For all panels, the measure of center is mean. Identify those arcade games from a 1983 Brazilian music video. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in A Package for Survival Analysis in S. Version 2.38 (2015); http//cran.r-project.org/package=survival. When neutralizing an acid, a simple acid base reaction has to occur. Extracellular thiol-assisted selenium uptake dependent on the x(c)- cystine transporter explains the cancer-specific cytotoxicity of selenite. HCl. The solution was stored over 7 days prior to use and filtered with a 0.45 m membrane filter (25CS045AN; Advantec). Number is an animal identifier number. By clicking Post Your Answer, you agree to our terms of service, privacy policy and cookie policy. J. Na 2 Se + 2 HCl H 2 Se + 2 NaCl The compound reacts with electrophiles to produce the selenium compounds. The optional white tile is to go under the titration flask, but white paper can be used instead. Suzuki, K. T. & Ogra, Y. Metabolic pathway for selenium in the body: speciation by HPLC-ICP MS with enriched Se. Acid-Base Reactions & Neutralization | Overview & Examples, Titration Curves Graph & Function | How to Read a Titration Curve. Schecter, A., Shanske, W., Stenzler, A., Quintilian, H. & Steinberg, H. Acute hydrogen selenide inhalation. Similarly, sodium selenide is readily oxidized to polyselenides, a conversion signaled by off-white samples. HCl can also be neutralized with baking soda. [1], Sodium hydroselenide is slightly reducing. Cancer Cell 163, 506519 (2015). Sodium selenide reacts with acids to produce toxic hydrogen selenide gas. You can do dozens of chemistry experiments at home! c, Cleaved caspase 3 (CC3) staining in MDAMB231 and U251cells following KO with guides against SEPHS2 at 10 days after viral transduction. The full electronic configuration is expected to include the sub-shells s, p, d, up to element . and D.K. As soon as the reaction with the hydroxide took place, the colorless indicator crimsoned with delight. Talanta 153, 306331 (2016). Thank you for visiting nature.com. If they meet without a Chemists supervision, it bodes only disaster! In chemistry, neutral means not being an acid or a base. Extended Data Fig. Can you write oxidation states with negative Roman numerals? Hum. g, Immunoblots of GPX4 in cells transduced as indicated. Internet Explorer). Many such molecules react with acids and other compounds, and that's a big chunk of organic chemistry. Example: What is the formula of the compound formed between sodium (group 1) and selenium (group 16) sodium valency = group number = 1 selenium valency = 18 - group number = 2. All other authors declare no competing interests. 4 Expression of SEPHS2 in various types of tumor and normal tissues. As a result, when mixed with HCl (acid), it will react to form salt and water, both neutral substances. The X-axis and y-axis of Flow cytometry density plots were designated as Annexin V-FITC and PI, respectively. contracts here. Bersuker, K. et al. 4. . For all panels, *p<0.05, **p<0.01, and ***p<0.001 (students two-tailed t test). c, Immunoblots of SLC7A11 in cells transduced with Cas9/sgRNAs targeting SLC7A11 or non-targeting sgRNA. Although, to be fair, we should note that only 1% of this water is suitable for consumption. Molarity is the number of moles in a liter of solution. 3 ). d, Quantification of CC3 positive cells over total cells in CTRL and SEPHS2 deficient MDAMB231 and U251. Harrington, D. P. & Fleming, T. R. A class of rank test procedures for censored survival data. and D.K. Each value was normalized to that of unconditioned medium. Extended Data Fig. Enrolling in a course lets you earn progress by passing quizzes and exams. Yang, W. S. et al. According to one article, "not much was known about which selenium compounds to approve for use in animal feeds when the decisions were made back in the 1970s .. At the time the regulatory action was taken, only the inorganic selenium salts (sodium selenite and sodium selenate) were available at a cost permitting their use in animal feed. We just need to add sodium hydroxide (NaOH), a strong base, into the mix. - khaverim Feb 1, 2016 at 4:05 As we can see, the result of the interaction of two highly aggressive compounds is table salt and water compounds that are ultimately harmless, even beneficial, to human beings. Baking soda is often used to neutralize HCl in the event of a chemical spill. Rev. Doll, S. et al. The reaction between hydrochloric acid and sodium hydroxide is below. Values are relative to cells cultured in 100% growth media, set at 1.0. c, Viability of control, SEPHS2, GPX4, and SEPSECS deficient MDAMB231 cells after being cultured in hypoxic condition (1% O2) for 48hr. Write a word equation and a symbol equation. volume2,pages 603611 (2020)Cite this article. What follows here assumes that teachers have judged the class to be capable of doing this experiment using a burette with reasonable expectation of success. In the meantime, to ensure continued support, we are displaying the site without styles Dohoon Kim. Synthesis and fundamental reactions [ edit] Sodium selenite usually is prepared by the reaction of selenium dioxide with sodium hydroxide: [1] By the direction of the course of the reaction, it is irreversible. Carbon Dioxide in Water Solubility & Reaction | Is CO2 Soluble in Water? https://doi.org/10.1038/s42255-020-0224-7. Xu, X. M. et al. For all panels, the measure of center is mean. Article C5.4.7 describe and explain the procedure for a titration to give precise, accurate, valid and repeatable results, 6 Titration of a strong acid and strong alkali to find the concentration of the acid using an appropriate pH indicator, 7 Production of pure dry sample of an insoluble and soluble salt, C5 Monitoring and controlling chemical reactions, C5.1b describe the technique of titration, PAG 6 Titration of a strong acid and strong alkali to find the concentration of the acid using an appropriate pH indicator. Students should be able to describe how to make pure, dry samples of named soluble salts from information provided. Natl Acad. ICP-MS-based experiments for selenite measurements were conducted by M.S. Sodium selenate is leached in water and is reduced to sodium selenide, which is then oxidized by blowing in air through the solution. Nucleic Acids Res. What is the thermochemical equation for the combustion of benzene? C CHEMISTRY; METALLURGY; C07 ORGANIC CHEMISTRY; C07J STEROIDS; C07J41/00 Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring; C07J 3. Acidic Solutions Properties & Examples | What is an Acidic Solution? HCl is in almost all cases already aqueous for common chemistry, mostly dissociated into $\ce{H^+} + \ce{Cl^-}$ because it is a strong acid, which means water is the primary solvent, not HCl. Nature 520, 5762 (2015). Tumor subtypes having over 2-fold SEPHS2 expression in tumor than normal and q-value less than 0.01 indicated with red. The reaction is accompanied by a thermal effect, and the amount of heat released is 57.3kJ/mol. In this study, the removal/precipitation of selenium with sodium sulfide from initially weakly acidic sulfate solutions containing 300 mg/L of selenium(IV) at 23 C was studied. 18 October 2022, npj Science of Food To calculate molarity, divide the number of moles by the volume. In one process charcoal is used as reductant. Sodium hydroselenide is a chemical compound, an inorganic salt; each unit consists of one sodium, one selenium, and one hydrogen atom. Try refreshing the page, or contact customer support. Discover a wealth of optimised experiments and demonstrations for your classroom. Sodium hydroxide (NaOH) mixed with hydrochloric acid (HCl), a simple acid base reaction, results in the formation of salt and water. NOTE: ALL NUMBERS IN FORMULAS SHOULD BE WRITTEN AS SUBSCRIPTS. Despite the fact that the solid-state is yellow, the solution is colourless. Read our privacy policy. In a full sentence, you can also say HCl (hydrogen chloride) reacts with Na2Se (Sodium selenide; Selenodisodium; Disodio selenide) and produce NaCl (sodium chloride) and H2Se (Dihydrido selenium; Dihydrogen selenide; Hydrogen selenide; Selenium hydride; Dihydridoselenium). This should produce a white crystalline solid in one or two days. The toxicities of mixtures of 50 M sodium selenide plus 20 or 40 M metal ions were compared. With alkyl halides, one obtains a variety of organoselenium compounds: Organotin and organosilicon halides react similarly to give the expected derivatives: This inorganic compoundrelated article is a stub. Highly-concentrated acid causes severe burns if it encounters skin, mucous membranes or eyes, but is present in the human stomach at a concentration of around0.5%. For c,d n=3 independent experiments; error bars are S.D. Values are relative to the same cell lines expressing nontargeting (CTRL) guide (=1.0), (b) Light microscope images of MDAMB231 and MCF10A cells subjected to CTRL or SEPHS2 KO. F. Fher, "Sodium Selenite" in Handbook of Preparative Inorganic Chemistry, 2nd Ed. Once the pH is neutral (a pH of 7), then we know that all of the hydrochloric acid has been turned into salt water. Scale bar is 100m. For all panels, *p<0.05 and **p<0.01 (students two-tailed t test). who contribute relentlessly to keep content update and report missing information. This inorganic compoundrelated article is a stub. Redox imbalance in cystine/glutamate transporter-deficient mice. - Formula & Reactions, Using Ammonium Hydroxide & Sodium Hydroxide on Salts, Using Ammonium Hydroxide & Sodium Hydroxide on Metals & Metal Oxides, Role of Bacteria in Gastrointestinal Health, Fad Diets: Potential Dangers & Alternatives, Compaction in Geology: Definition & Examples, Allochthonous Material in Ecology: Definition & Impact, Sulfite: Uses, Formula, Side Effects & Allergy Symptoms, What is a Drought? a, A list of selenium transporter candidates examined in the focused screen, rationale for candidacy, and references. Scale bar=20m. [5], Sodium selenite has been proposed as an effective suicide agent. However, the dishes should not be allowed to dry out completely, as this spoils the quality of the crystals. We can do this with a pH meter or with pH indicator paper. Toxicol. Resonance is a stabilizing, energy minimizing effect, but it does not render every molecule with resonance unreactive. #color(white)(aaaaaaaaaaaaa/a)color(red)(uarr)# Asking for help, clarification, or responding to other answers. 3 d , the FeS/NC in DME electrolyte achieved remarkable reversible capacity of 520, 485, 455, 441, 427, 400, and 519 mAh g -1 at 0.1, 0.2, 0.5, 1.0, 2.0 and 5.0 A g -1 . b, Viability of control and SLC7A11 KO U251 cells treated with 12M of sodium selenite for 48hr. c, SEPHS2 immunoblots from the cells used in b. Once we are almost finished adding the 2.5 L of sodium hydroxide, we start checking the pH. Correspondence to 10ae b, Percentages of Annexin V+/PI- and Annexin V+/PI+cells. Using a small funnel, pour a few cubic centimetres of 0.4 Mhydrochloric acid into the burette, with the tap open and a beaker under the open tap. Open Access Breast Cancer Res. Open Access articles citing this article. How are we supposed to turn hydrochloric acid into salt water? Practical Chemistry activities accompanyPractical PhysicsandPractical Biology. i, Viabilities of noncancer (immortalized) and cancer lines following KO with guides against SEPHS1 (blue bars) for 9 days. Students need training in using burettes correctly, including how to clamp them securely and fill them safely. Salt solutions can be crystallised to produce solid salts. The reaction continues till the very end, until the reacting substances are completelyconsumed. & Zhang, F. Improved vectors and genome-wide libraries for CRISPR screening. We've added a "Necessary cookies only" option to the cookie consent popup, I'm trying to verify the integrity of my cheap "24k gold" leaf. Amoedo, N. D., Obre, E. & Rossignol, R. Drug discovery strategies in the field of tumor energy metabolism: limitations by metabolic flexibility and metabolic resistance to chemotherapy. Therefore, molarity is equal to moles divided by volume. You can help Wikipedia by expanding it. Sodium selenide reacts with acids to produce toxic hydrogen selenide gas. You may need to evaporate the solution in, say, 20 cm. Titration is used to determine, accurately, the volumes of solution required to reach the end-point of a chemical reaction. Find the concentration of a solution of hydrochloric acid. The solution spits near the end and you get fewer crystals. PubMedGoogle Scholar. [2] Oxidation of this anion gives sodium selenate, Na2SeO4. Add the hydrochloric acid to the sodium hydroxide solution in small volumes, swirling gently after each addition. Now, lets acquaint ourselves with hydrochloricacid. Values are relative to the cells treated with vehicle (=1.0). National Center for Biotechnology Information. These reactions typically take place between a strong acid and strong base. Hydrochloric acid (HCL) is formed by joining a single hydrogen atom to a single chlorine atom through a covalent bond. Filling the burette, measuring out the alkali into the flask, and titrating it until it is neutralised takes about 20 minutes, with false starts being likely for many groups. Ingold, I. et al. (d and e) Micrographs of serial xenograft tumor sections stained with CA9, GPX4, KI67 antibodies and in situ hybridized with SEPHS2 RNA probe. We should also only work with these chemicals in a well-ventilated area. Cancer Ther. Benzoic Acid Structure & Formula | What is Benzoic Acid? The best answers are voted up and rise to the top, Not the answer you're looking for? . Hangauer, M. J. et al. Open Access Continue until the solution just turns from yellow-orange to red and record the reading on the burette at this point. This colourless solid is prepared by the reaction of selenium with a solution of sodium in liquid ammonia at 40 C. In this experiment a pipette is not necessary, as the aim is to neutralise whatever volume of alkali is used, and that can be measured roughly using a measuring cylinder. g, Viability of control and SLC7A11 KO U251 cells treated with vehicle or 12M sodium selenite for 72hr. This is discussed further below, but what follows here assumes that you have judged the class to be capable of doing this experiment using a burette with reasonable expectation of success. (2017) GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Therefore, it is classified as a hazardous waste and must be disposed of properly. d, Map of wild type SEPHS2 and CRISPR resistant mutant SEPHS2_U60C. This means that your reactants will be sodium metal and hydrochloric acid, since these are the substances that are being transformed to form salt and hydrogen gas. d, Total thiol quantification of 24hr conditioned media from control and SLC7A11 KO U251 cells. Ciriello, G. et al. USA 106, 1140011405 (2009). a, Viability of cell lines following KO with guides against SEPHS2 for 9 days. The acid and base react to form a salt and water. The compound reacts with electrophiles to produce the selenium compounds. To evaluate sodium ion transfer capability in different electrolytes, the rate performance was tested at current densities ranging from 0.1 to 5.0 A g-1. Hydrochloric acid (HCl), a strong acid, is composed of a single hydrogen atom and a single chlorine atom bonded together covalently. Pure HCl under ambient conditions is actually a gas (thus certainly not a pure liquid solvent). And its equation reads asfollows: Hydrochloric acid and sodium hydroxide interact, resulting in salt and a release ofheat.
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